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Entering the New Era of Perfusion

Built on LivaNova’s 50-years of proven safety and reliability, Essenz™ Perfusion System supports the Perfusionist and the entire heart team in delivering truly patient-centric perfusion therapies and continuously improve clinical practice.

Discover the Essenz™ Perfusion System

An integrated next generation perfusion system that provides value both inside and outside the OR.

We stand behind you

Supporting Perfusionists as They Support Patients

Safe and Reliable



Flexible and Efficient

The Essenz™ Perfusion System is built on a 50-year legacy of trusted partnership with perfusionists. It is designed to meet evolving standards of safety and reliability, to deliver life-saving care to patients.

Essenz Heart-Lung Machine

Innovation starts from an unmatched foundation:

  • Essenz is built on proven S5 reliability and a reputation for safe cardiopulmonary bypass management

State-of-the-art safety precautions:

  • Each pump is controlled individually: 1 knob = 1 pump
  • The cockpit and the Patient Monitor are connected but operate separately
  • Redundant and individual safety mechanisms
  • Automated sensor checks
  • Integrated warning system based on user-defined thresholds

State-of-the-art on-site support and escalation process:

  • With the Essenz™ Focus service proposition, experienced sales and service teams are available in more than 100 countries, to meet planned or unplanned needs

The combination of accurate sensing technology, the mast mounted pumps and embedded clinical logic allows perfusionists to deliver patient-tailored perfusion therapies

Accurate sensing technology and official formulas to support the implementation of Goal-Directed Perfusion (GDP) therapy:1

  • Reliability of the Essenz In-Line Blood Monitor measured parameters
  • Implementation of real-time tailored patient care
  • Focus on the metabolic needs of each patient

1. Goal-Directed Perfusion to reduce Acute Kidney Injury: A Randomized Trial Ranucci M. et al. J Thorac Cardiovasc Surg. 2018 Nov;156(5):1918-1927.e2.

Patient Monitor with embedded clinical logic to support data-driven clinical decision making:

  • Intra-operative Quality Indicator Threshold and GDP modules support clinicians by allowing them to individualise the patient management strategy during the case
  • Quality Indicators, developed alongside global perfusionists, can be used to monitor patient parameters variation against thresholds

Modular system:

  • Mast-mounted pumps allow to optimize the position of the disposables (oxy and tubings set), minimizing priming volumes and thus reducing hemodilution2


2. Inflammatory response to cardiopulmonary bypass: mechanisms involved and possible therapeutic strategies. - Wan S, LeClerc JL, Vincent JL.Chest. 1997 Sep;112(3):676-92. doi: 10.1378/chest.112.3.676.PMID: 9315800

The Essenz Perfusion System supports clinical requirements through a combination of state-of-the-art technology and a user-friendly experience, designed and validated with perfusionists.

First case with Essenz at San Donato Hospital, Italy
  • The intuitive user interface on all monitors is developed according to the latest medical device standards, with a soothing background with white numbers to aid visibility


[Image: San Donato Hospital, Italy]

  • Continuously recorded data and events on the Essenz Patient Monitor enhance traceability and support the perfusionist during and after the cardiopulmonary bypass procedure
  • Essenz Perfusion System is built to accommodate a stream of future software features and functionalities, making it a valuable long term investment

The fully integrated Essenz Perfusion System enables great efficiency in managing the procedure and connects to the wider hospital infrastructure.

  • Flexible selection of HW and disposable components and relevant positions
  • Advanced profile management
  • Integrated system with advanced cable management and mast-mounted design to minimize clutter, improve visibility and make it easy to clean the area
  • Cockpit provides one central view and control, minimizing distractions
  • Essenz seamlessly integrates with OR external devices and hospital information system
  • The System also supports hospitals in meeting cyber and patient data security requirements

The Wisdom of Breath and Beat

What is the New Era of Perfusion?

With technology advancements and an increased focus on patient outcomes, perfusion and the role of the perfusionist are changing and entering a New Era.

Perfusionists are at the center of the New Era of Perfusion, and have driven every step of our journey developing the Essenz Perfusion System.

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Focused Service Support

Essenz™ Focus is the realization of the value we offer with the Essenz System:

  • Focus on our customers
  • Focus on our technology
  • Focus on perfusion

It enables our customers to focus on what matters to them: the patient.

Discover Essenz Focus

Experience the Essenz Perfusion System

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Safety Information

Summary of Safety & Performance Information for Essenz™ In-Line Blood Monitor

Heart-Lung Machine with Integrated Essenz In-Line Blood Monitor (ILBM)

The Essenz Heart-Lung Machine is  intended  to  perform,  control,  monitor  and  support  extracorporeal blood  circulation replacing  the  mechanical pumping  function  of  the  heart,  monitoring  and  regulating physiologic parameters  during  procedures  requiring extracorporeal circulation. 

Essenz Patient Monitor
The Essenz Patient Monitor software is a modularly structured software program package that is exclusively used with LivaNova heart-lung machines. The system allows detailed recording of perfusion data during cardiopulmonary bypass procedures as well as the processing and evaluation of this data. The data may be recorded automatically or entered manually. The LivaNova Perfusion System Monitor is a panel PC intended to be exclusively used with LivaNova heart lung machines as a base and user interface for the Essenz Patient Monitor software. 

CONTRAINDICATIONS: No contraindications are  known  if  the  devices are  used  for  the  purpose described  and  in  accordance  with  the  stated  operating conditions. Do not use the devices for any purpose other than indicated. 
WARNINGS: The devices must be used in accordance with the instructions for use provided.  For a complete listing of warnings please refer to the Instructions for Use. Medical intervention and therapeutic procedure must not be based solely on the Essenz Patient Monitor perfusion records (reports). 

PRECAUTIONS: Federal law (U.S.A.) restricts these devices to sale by or on the order of a physician. For a complete listing of precautions/cautions please refer to the Instructions for Use. The devices should be used by qualified and skilled personnel, able to follow the indications and instructions for use contained in  the information  provided  by  the  manufacturer.

Essenz In-Line Blood Monitor and B-Capta Blood Gas Monitor are clinically equivalent in terms of safety and performance as they have the same technology and intended use.  Not approved in all geographies, consult your labeling. Please visit the LivaNova website  to  receive  instructions  for  use  containing  full  prescribing information including indications, contraindications, warnings, precautions and adverse events.

Legal Manufacturer: 
LivaNova Deutschland
Lindberghstrasse 25

Sorin Group Italia S.r.l. 
Via Statale 12 Nord, 86 
41037  Mirandola (MO) ITALY