Choose a country and language

DE Flag

Germany

German
GB Flag

United Kingdom

English
US Flag

United States

English
Choose another country or region to see content specific to your location.

A Different Approach to Difficult-to-Treat Depression.

Get Well and Stay Well with VNS Therapy®

The VNS Therapy® System is indicated for the treatment of chronic or recurrent depression in patients who are in a treatment-resistant or treatment-intolerant major depressive episode.

Couple at beach
1 in 3 people with depression image

You Are Not Alone

Depression is the second most common mental health disorder in Europe - with 21 million people affected.

Around 50% of all people with depression will experience a chronic or recurrent course of illness for which long-term treatment is recommended.

What is Difficult-To-Treat Depression?

Difficult-to-Treat Depression (DTD) is a depression that continues to cause a significant burden despite usual treatment efforts.

People with difficult-to-treat depression can experience

Poor Quality of Life icon

Poor quality of life

Difficulties with Daily Functioning icon

Difficulties with daily functioning

social and work challenges icon

Social and work challenges

Physical Health Conditions icon

Other mental and physical health conditions

patient and care taker icon

Increased hospitalisations

Increased Use of Healthcare Services

Increased use of healthcare services

If you are struggling with depression (unipolar or bipolar) that is difficult to treat and traditional treatments have failed to provide you with relief, there is another way forward.

Man with VNS Therapy device
A Different Approach

VNS Therapy® for Difficult-to-Treat Depression

The VNS Therapy® System is indicated for the treatment of chronic or recurrent depression in patients who are in a treatment-resistant or treatment-intolerant major depressive episode.

VNS Therapy® is a non pharmacological treatment and stands for Vagus Nerve Stimulation Therapy. The vagus nerve is the longest nerve in your body and is the main nerve that connects your brain to the rest of your body.

What makes VNS Therapy effective:

  • VNS Therapy modulates established pathways involved in depression.
  • VNS Therapy works by regularly transmitting small electrical signals from a neurostimulator (similar to a pacemaker) through a thin lead under your skin to your vagus nerve in the neck.
  • Through these small electrical signals, VNS Therapy has shown to improve depression symptoms.

There’s Safety in Our Numbers
VNS Therapy® is CE marked and has been extensively studied across multiple conditions
25+

Years of patient experience with VNS Therapy technology

100,000+

Patients implanted across multiple diseases

Real People. Real Stories.

Mary's Journey with VNS Therapy®

Michael's Journey with VNS Therapy®

Get well and stay well with VNS Therapy®

Find out more about VNS Therapy