Entering the New Era of Perfusion

Built on LivaNova’s 50-year legacy of safety and reliability, EssenzTM supports the Perfusionist in doing what is best for each patient, and allows the entire heart team to continuously improve their clinical practice.

We stand behind you

Supporting Perfusionists as They Support Patients

Safe and Reliable



Flexible and Efficient

The Essenz Perfusion System is built on a 50-year legacy of trusted partnership with perfusionists. It is designed to meet evolving standards of safety and reliability, to deliver life-saving care to patients.

S5 Heart-Lung Machine

Built on proven S5 reliability and a reputation for safe cardiopulmonary bypass management

State-of-the-art safety precautions:

  • Each pump is controlled individually: 1 knob = 1 pump
  • The cockpit and the Patient Monitor are connected but operate separately
  • Redundant and individual safety mechanisms
  • Automated sensor checks

Experienced sales and service teams available in more than 100 countries to meet planned or unplanned needs

The combination of accurate sensing technology and mast-mounted pumps allows perfusionists to deliver patient-tailored perfusion therapies.

Accurate sensing technology and a Patient Monitor to support data-driven clinical decision making1


1. Lukaszewski M et al., "The use of data science to analyse physiology of oxygen delivery in the extracorporeal circulation" BMC Cardiovasc Disord. 2019;19(1):292

Goal-Directed Perfusion implementation to provide insightful data through:2

  • Official formulas
  • Complete product offering


2. Goal-Directed Perfusion to reduce Acute Kidney Injury: A Randomized Trial Ranucci M. et al. J Thorac Cardiovasc Surg. 2018 Nov;156(5):1918-1927.e2.  doi.org/10.1016/j.jtcvs.2018.04.045

Mast-mounted pumps allow to optimize the position of the disposables (Oxy and tubings set), minimizing priming volumes and thus reducing hemodilution3


3. Inflammatory response to cardiopulmonary bypass: mechanisms involved and possible therapeutic strategies. - Wan S, LeClerc JL, Vincent JL.Chest. 1997 Sep;112(3):676-92. doi: 10.1378/chest.112.3.676.PMID: 9315800

The Essenz Perfusion System supports clinical requirements through a combination of state-of-the-art technology and a user-friendly experience, designed and validated with perfusionists.

First case with Essenz at San Donato Hospital, Italy

The intuitive user interface on all monitors is developed according to the latest medical device standards, with a soothing background with white numbers to aid visibility


[Image: San Donato Hospital, Italy]

Continuously recorded data and events on the Essenz Patient Monitor enhance traceability and support the perfusionist during and after the cardiopulmonary bypass procedure

Essenz Perfusion System is built to accommodate a stream of future software features and functionalities, making it a valuable long term investment

The fully integrated Essenz Perfusion System enables great efficiency in managing the procedure and connects to the wider hospital infrastructure.

The versatile system can be adapted to the individual needs of patients, workflows, and users

  • Flexible selection of hardware and disposable components and relevant positions
  • Advanced profile management

Ergonomic design creates an efficient experience:

  • Advanced cable management and mast-mounted design minimize clutter and make it easy to clean the area
  • Cockpit provides one central view and control, minimizing distractions

Essenz seamlessly integrates with OR external devices and hospital information system

The System also supports hospitals in meeting cyber and patient data security requirements

The Wisdom of Breath and Beat

Discover the Essenz Perfusion System

State-of-the-art heart-lung-machine with embedded Patient Monitor for tailored patient care strategies and accurate sensing technology for data-driven decision making


Experienced sales and service team for timely support


Essenz provides value both inside and outside the OR.


What is the New Era of Perfusion?

With technology advancements and an increased focus on patient outcomes, perfusion and the role of the perfusionist are changing and entering a New Era.

Perfusionists are at the center of the New Era of Perfusion, and have driven every step of our journey developing the Essenz Perfusion System.

Learn More

Discover Essenz Focus

Essenz Focus is the realization of the value we offer with the Essenz System:

  • Focus on our customers
  • Focus on our technology
  • Focus on perfusion

It enables our customers to focus on what matters to them: the patient.

Discover Essenz Focus

Experience the Essenz Perfusion System

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Safety Information

Summary of Safety & Performance Information for Essenz Perfusion System

Please note the Essenz information is available in selected geographies only.


Heart-Lung Machine

Devices  are  intended  to  perform,  control,  monitor  and  support  extracorporeal  blood  circulation replacing  the  mechanical pumping  function  of  the  heart,  monitoring  and  regulating  physiologic parameters  during  procedures  requiring extracorporeal circulation.  

US: Essenz HLM is intended to be used during cardiopulmonary bypass for procedures lasting six (6) hours or less.

Essenz Patient Monitor

The Essenz Patient Monitor software is a modularly structured software program package that is exclusively used with LivaNova heart-lung machines. The system allows detailed recording of perfusion data during cardiopulmonary bypass procedures as well as the processing and evaluation of this data. The data may be recorded automatically or entered manually. The LivaNova Perfusion System Monitor is a panel PC intended to be exclusively used with LivaNova heart lung machines as a base and user interface for the Essenz Patient Monitor software.

CONTRAINDICATIONS: No contraindications  are  known  if  the  devices are  used  for  the  purpose  described  and  in  accordance  with  the  stated  operating conditions. Do not use the devices for any purpose other than indicated.

WARNINGS: The devices must be used in accordance with the instructions for use provided.  For a complete listing of warnings please refer to the Instructions for Use. Medical intervention and therapeutic procedure must not be based solely on the Essenz Patient Monitor perfusion records (reports).

PRECAUTIONS: Federal law (U.S.A.) restricts these devices to sale by or on the order of a physician. For a complete listing of precautions/cautions please refer to the Instructions for Use. The devices should be used by qualified and skilled personnel, able to follow the indications and instructions for use contained in  the  information  provided  by  the  manufacturer.

Not approved in all geographies. Please contact us through the LivaNova website  to  receive  instructions  for  use  containing  full  prescribing information including indications, contraindications, warnings, precautions and adverse events.

Legal Manufacturer:

LivaNova Deutschland

Lindberghstrasse 25D-80939

Munich, Germany

Essenz Patient Monitor distributed in the US by:

LivaNova USA

14401 W 65th Way

Arvada, CO 80004, USA

Distributed in Canada by: 

LivaNova Canada Inc. 

280 Hillmount Road, Unit 8 

Markham, ON  L6C 3A1, Canada