This website is intended for healthcare professionals in the United Kingdom. VNS Therapy™ for drug-resistant epilepsy is not available in all regions - please refer to your country-specific labelling.
VNS Therapy™ - AspireSR™
VNS Therapy™ can lead to fewer seizures, shorter seizures and better recovery after seizures.
AspireSR™- Advancing the treatment of drug-resistant epilepsy with responsive VNS Therapy™
- Proven efficacy and safety of VNS Therapy1
- Helps stop or shorten a seizure by responding to a rapid increase in heart rate, that may be associated with seizures2
- Helps prevent seizures by delivering treatment at regular intervals all day, every day2
- May reduce seizure duration and seizure severity and improve post-ictal recovery3
- Improves quality of life3
VNS Therapy™ works to control seizures in three ways
Normal Mode
Helps to reduce seizures
Stimulation is delivered at regular intervals all day, every day, to help reduce seizures16
AutoStim Mode
Responds to rapid increases in heart rate*
An extra dose of therapy is automatically delivered at the sign of a rapid increase in heart rate, which may be associated with seizures16
*Only available in Models 106, 1000 and 1000-D
VNS Therapy™ Magnet
Delivers on-demand treatment
Stimulation is manually delivered by swiping the VNS Therapy™ Magnet over the area of the device to help stop or shorten a seizure once it starts2,10
AspireSR™ detects and responds to rapid increases in heart rate, that may be associated with a seizure2
Over 60% of treated seizures ended during automatic stimulation†
The closer the stimulation to seizure onset, the shorter the seizure duration4
The change from regular to responsive VNS TherapyTM showed a reduction of seizure frequency
Based on the McHugh Classification of patients receiving VNS Therapy:
.webp?language=en-GB "McHugh-Responsive-VNS (2)")
12 out of 19 patients (41%) who had less than 50% seizure reduction with regular VNS Therapy reported more than 50% seizure reduction with responsive VNS Therapy following a battery change.
This study was a non-controlled retrospective analysis of data where the seizure reporting is an interpretation of patients and carers.
*Conventional VNS Therapy in this article refers to models before AspireSR without the cardiac based seizure detection and closed loop stimulation. **Responsive VNS Therapy in this article refers to AspireSR model.