VNS Therapy™ can lead to fewer seizures, shorter seizures and better recovery after seizures.
AspireSR™- Advancing the treatment of drug-resistant epilepsy with responsive VNS Therapy™
- Proven efficacy and safety of VNS Therapy1
- Helps stop or shorten a seizure by responding to a rapid increase in heart rate, that may be associated with seizures2
- Helps prevent seizures by delivering treatment at regular intervals all day, every day2
- May reduce seizure duration and seizure severity and improve post-ictal recovery3
- Improves quality of life3
Helps to reduce seizures
Stimulation is delivered at regular intervals all day, every day, to help reduce seizures16
Responds to rapid increases in heart rate*
An extra dose of therapy is automatically delivered at the sign of a rapid increase in heart rate, which may be associated with seizures16
*Only available in Models 106, 1000 and 1000-D
Delivers On-Demand Treatment
Stimulation is manually delivered by swiping the VNS Therapy™ magnet over the generator to help stop or shorten a seizure once it starts16
AspireSR™ detects and responds to rapid increases in heart rate, that may be associated with a seizure2
Over 60% of treated seizures ended during automatic stimulation†
The closer the stimulation to seizure onset, the shorter the seizure duration4
The change from regular to responsive VNS TherapyTM showed a reduction of seizure frequency
Based on the McHugh Classification of patients receiving VNS Therapy:
12 out of 19 patients (41%) who had less than 50% seizure reduction with regular VNS Therapy reported more than 50% seizure reduction with responsive VNS Therapy following a battery change.
This study was a non-controlled retrospective analysis of data where the seizure reporting is an interpretation of patients and carers.
*Conventional VNS Therapy in this article refers to models before AspireSR without the cardiac based seizure detection and closed loop stimulation. **Responsive VNS Therapy in this article refers to AspireSR model.
*Responsive VNS Therapy™ refers to VNS Therapy devices with AutoStim Mode enabled. Available in models 106 and 1000, 1000-D
†Individual study example (N=28/46). Results may vary.
1. Elliott R.E. et al. Epilepsy & Behavior, 20 (2011) 57–63 2. VNS Therapy System™ Epilepsy Physician’s Manual, January 2021, LivaNova, Houston, TX. 3. Orosz I. et al. Epilepsia, 55(10):1576–1584, 2014 4. Data on file, LivaNova, Inc., Houston, TX. 5. Hamilton, P., et al. (2018) Seizure 58:120-126. 16. VNS Therapy™ System Epilepsy Physician’s Manual April 2021, 76-0000-5600/8 (OUS)