AspireSR®
VNS Therapy can lead to fewer seizures, shorter seizures and better recovery after seizures.
AspireSR® detects and responds to rapid increases in heart rate that may be associated with a seizure1
In clinical trials, over 60% of seizures treated ended during automatic stimulation.
The closer the stimulation to seizure onset, the shorter the seizure duration2
VNS Therapy® controls seizures in 3 ways
Preventative
Normal Mode
Helps prevent seizures by delivering treatment at regular intervals all day, every day1
Responsive*
AutoStim Mode
Helps stop or shorten a seizure by responding to a rapid increase in heart rate, a proven seizure biomarker1,3,4
*Only available in models 106 and 1000
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On-Demand
Magnet Mode
Helps stop or shorten a seizure once it starts by passing the included VNS Therapy Magnet over the generator1
Responsive VNS Therapy* provides additional seizure reduction5
At 1 year following replacement with responsive VNS Therapy device in patients who were not already seizure-free with conventional VNS Therapy (n=17)
Responsive VNS Therapy devices include Normal Mode, Magnet Mode and AutoStim Mode. Conventional VNS Therapy devices include Normal Mode and Magnet Mode.
*Only available in models 106 and 1000
VNS Therapy® de-intensifies seizures and improves patient recovery after seizures
Reduction in duration of focal seizures3
62% REDUCTION in median seizure duration
(32 seconds v 85 seconds, in patients on VNS Therapy with AutoStim compared to patients' historical data)
AspireSR® is proven to improve quality of life2
Clinically meaningful and statistically significant improvements in overall QOL were seen at 3 months and continued to improve over time.
AspireSR® - Advancing the treatment of drug-resistant epilepsy
- Provides the proven long-term efficacy and safety of VNS Therapy
- Detects and responds to ictal tachycardia to stop seizures spreading in the brain
- May terminate seizures by delivering automatic stimulation when a seizure occurs
- May reduce seizure duration and seizure severity and improve post-ictal recovery
- Improves quality of life
References
1. VNS Therapy System® Epilepsy Physician’s Manual (US), May 2020, LivaNova USA, Inc. Houston, TX. 2. Data on file, LivaNova, Inc., Houston, TX. 3. Fisher RS, Afra P, Macken M, et al. Neuromodulation. 2016;19:188-195. 4. Hirsch M, Altenmüller DM, Schulze-Bonhage A. Epilepsia. 2015;56(10):1639-1647. 5. Datta P, Galla KM , Sajja K, et al. Epilepsy Behav. 2020;111:107280.