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AspireSR®

VNS Therapy can lead to fewer seizures, shorter seizures and better recovery after seizures.

AspireSR® VNS Therapy device
AspireSR® detects and responds to rapid increases in heart rate which may be associated with a seizure

AspireSR® detects and responds to rapid increases in heart rate that may be associated with a seizure1

In clinical trials, over 60% of seizures treated ended during automatic stimulation.

The closer the stimulation to seizure onset, the shorter the seizure duration2

VNS Therapy® controls seizures in 3 ways

Preventative - Normal Mode

Preventative

Normal Mode

Helps prevent seizures by delivering treatment at regular intervals all day, every day1

Responsive* AutoStim Mode

Responsive*

AutoStim Mode

Helps stop or shorten a seizure by responding to a rapid increase in heart rate, a potential seizure biomarker1,3,4

*Only available in models 106 and 1000

On-Demand Magnet Mode

On-Demand

Magnet Mode

Helps stop or shorten a seizure once it starts by passing the included VNS Therapy® Magnet over the generator1

Responsive VNS Therapy with AutoStim* provides additional seizure reduction

Responsive VNS Therapy* provides additional seizure reduction5

At 1 year following replacement with responsive VNS Therapy device in patients who were not already seizure-free with conventional VNS Therapy (n=17)

Responsive VNS Therapy devices include Normal Mode, Magnet Mode and AutoStim Mode. Conventional VNS Therapy devices include Normal Mode and Magnet Mode.

*Only available in models 106 and 1000

VNS Therapy de-intensifies seizures and improves patient recovery

VNS Therapy® de-intensifies seizures and improves patient recovery after seizures

Reduction in duration of focal seizures3

62% REDUCTION in median seizure duration

(32 seconds v 85 seconds, in patients on VNS Therapy with AutoStim compared to patients' historical data)

AspireSR® is proven to improve quality of life

AspireSR® is proven to improve quality of life2

Clinically meaningful and statistically significant improvements in overall QOL were seen at 3 months and continued to improve over time.

AspireSR® - Advancing the treatment of drug-resistant epilepsy

AspireSR® - Advancing the treatment of drug-resistant epilepsy

  • Provides the proven long-term efficacy and safety of VNS Therapy
  • Detects and responds to ictal tachycardia to stop seizures spreading in the brain
  • May terminate seizures by delivering automatic stimulation when a seizure occurs
  • May reduce seizure duration and seizure severity and improve post-ictal recovery
  • Improves quality of life

AspireSR® Technical Sheet

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MRI Safety

The latest VNS Therapy® technology with expanded MRI access allows patients to obtain quality MRI scans

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References
1. VNS Therapy System® Epilepsy Physician’s Manual (US), May 2020, LivaNova USA, Inc. Houston, TX. 2. Data on file, LivaNova, Inc., Houston, TX. 3. Fisher RS, Afra P, Macken M, et al. Neuromodulation. 2016;19:188-195. 4. Hirsch M, Altenmüller DM, Schulze-Bonhage A. Epilepsia. 2015;56(10):1639-1647. 5. Datta P, Galla KM , Sajja K, et al. Epilepsy Behav. 2020;111:107280.